Space Travel News
EPIDEMICS
Decade since Ebola, Sierra Leone fights another deadly fever
Decade since Ebola, Sierra Leone fights another deadly fever
By Alice CHANCELLOR, Saidu BAH
Kenema, Sierra Leone (AFP) July 10, 2024

Rummaging in the darkness of a tiny mud and thatch home in eastern Sierra Leone, ecologist James Koninga plucks a metal rat trap from under a collapsed bedframe.

The 62-year-old belongs to a group of researchers tracking the deadly Lassa fever, a viral haemorrhagic illness endemic in several West African countries and transmitted by infected rats.

Koninga knows all too well what is at stake -- he spent a gruelling 20 days in hospital with a Lassa-induced fever, headache and diarrhoea as a young researcher 30 years ago.

"I thought I was going away, I was going to die," he said.

Ten years ago, the haemorrhagic Ebola virus devastated this region, killing over 11,000 people across Guinea, Sierra Leone and Liberia.

Sierra Leone has not recorded an Ebola case since the outbreak ended in 2016, thanks partly to a vaccine rollout.

In Kenema district, an early Ebola epicentre, scientists are using the lessons learned a decade ago to try to stop Lassa fever in its tracks.

With an overall fatality rate of one percent, Lassa is nowhere near as deadly as Ebola, which kills on average 50 percent of sufferers, according to the World Health Organization.

But one in five Lassa infections can result in severe illness with a fatality rate of 15 percent.

While cases have largely plateaued in Sierra Leone, researchers are seeing a spread beyond traditional Lassa hotspots.

There is no licensed vaccine and only limited treatment, with the scars of Ebola preventing many from seeking early life-saving help.

- Living with rats -

Monitoring the rodent population is crucial in remote villages like Mapuma, where some 20 houses lie enveloped by dense forest.

"Rats burrow inside the houses for shelter," explained Koninga, donning a face shield and gloves.

Humans usually contract Lassa virus after having contact with the urine, saliva or droppings of infected rats.

"If people come in from the bush with cuts on them and lie on the bed, they could be infected."

Proximity to the forest, rudimentary mud construction, and uncovered grain and water storage make the dwellings "five-star hotels" for rats, said Lansana Kanneh, 58, field supervisor at the region's Kenema Government Hospital (KGH).

"Food is scarce for these people so sometimes they even eat the food that has been partially eaten by the rodent," he added.

Trappers can find up to 20 rats per day in some villages.

After identifying if the rodents are the Lassa-carrying Mastomys variety, samples are collected for analysis.

The rats then receive an injection that prevents viral transmission before being released.

Lassa virus infects between 100,000 and 300,000 people annually in West Africa, killing roughly 5,000, according to the Africa Centres for Disease Control and Prevention.

But the figures likely underestimate the true scale given surveillance challenges.

Admissions to the Lassa unit at KGH -- Sierra Leone's only dedicated treatment centre -- have declined in the past decade.

Patients normally arrive in the 14-bed isolation ward during the dry season from November to May, but this once-predictable pattern is increasingly uncertain.

- 'Lassa blood' -

"Now we see cases year-round," said Donald Grant, head of the KGH Lassa fever programme.

The team are also noticing Lassa beyond traditionally endemic zones, with Grant suspecting an improvement in testing as well as deforestation driving rodents into closer contact with humans.

Over the past decade, KGH has also seen an alarming uptick in Lassa patient mortality, which now stands at over 50 percent.

"We've seen a lot of these cases coming in in their late stages," said Kanneh.

"Sometimes they only spend 24 to 48 hours in the hospital, and they die."

Rapid detection is the key to survival, but non-specific febrile symptoms mean Lassa is commonly misdiagnosed as malaria, cholera or typhoid.

Hours-long journeys on dirt roads prevent many from seeking treatment.

As does the trauma from Ebola, which killed some 4,000 Sierra Leoneans.

"The community people thought that Ebola was brought by the health workers," Kanneh said, explaining that a lingering mistrust contributed to reduced admissions.

A KGH team raises awareness in local communities about seeking rapid help and ensuring good domestic hygiene.

It is a message well-received by Musa Mosoh, a 53-year-old Lassa survivor who lost seven family members to the illness.

As the morning rain fell in his village of Panguma -- a Lassa red zone -- Mosoh recalled how his family had faced stigma from the community.

"Now... people have got the understanding we are not from Lassa blood, it's just a sickness."

Mosoh tells those with a continuous fever or headache to go straight to the hospital, and even keeps cats to repel any virus-carrying rodents.

Grant, the doctor, is hopeful of a vaccine in the next few years.

Participants in Nigeria and Liberia are currently being given the first-ever Lassa vaccine to reach phase two trials -- the midway point of testing in humans.

But Grant still urges caution.

Ebola "taught us a lesson that we need not wait until that critical moment that it overwhelms all of us," he said.

"We need to act now."

Related Links
Epidemics on Earth - Bird Flu, HIV/AIDS, Ebola

Subscribe Free To Our Daily Newsletters
Tweet

RELATED CONTENT
The following news reports may link to other Space Media Network websites.
EPIDEMICS
Decade since Ebola, Sierra Leone fights another deadly fever
Kenema, Sierra Leone (AFP) July 4, 2024
Rummaging in the darkness of a tiny mud and thatch home in eastern Sierra Leone, ecologist James Koninga plucks a metal rat trap from under a collapsed bedframe. The 62-year-old belongs to a group of researchers tracking the deadly Lassa fever, a viral haemorrhagic illness endemic in several West African countries and transmitted by infected rats. Koninga knows all too well what is at stake - he spent a gruelling 20 days in hospital with a Lassa-induced fever, headache and diarrhoea as a young ... read more

EPIDEMICS
EPIDEMICS
Volunteer Crew to Exit NASA's Simulated Mars Habitat After 378 Days

This desert moss has the potential to grow on Mars

Crew inside NASA's Mars habitat simulator to exit after more than a year

NASA Parachute Sensor Testing Could Make EPIC Mars Landings

EPIDEMICS
Eye Test for Lunar Impact Surveyor

NASA names Andre Douglas as backup Artemis II crew member

Moon 'swirls' could be magnetized by unseen magmas

iSpace lunar lander RESILIENCE achieves test milestone

EPIDEMICS
NASA's Juno Observes Lava Lakes on Jupiter's Moon Io

Understanding Cyclones on Jupiter Through Oceanography

Unusual Ion May Influence Uranus and Neptune's Magnetic Fields

NASA's Europa Clipper Arrives in Florida for Launch Preparation

EPIDEMICS
New Method to Enhance Microbe Viability for Space and Extreme Environments

MIT engineers find a way to protect microbes from extreme conditions

Scientists reveal the density differences of sub-Neptunes due to resonance

Organic material from Mars reveals the likely origin of life's building blocks

EPIDEMICS
SpaceX completes Starlink launch, brings Direct to Cell satellite total to 103

Firefly Aerospace Successfully Launches Eight CubeSat Satellites

Starliner undergoing thruster testing before indefinite return flight

Space Pioneer Issues Apology After Engine Test Explosion

EPIDEMICS
Chinese Scientists Develop Novel Rosa Roxburghii Varieties via Space Breeding

Shenzhou 18 Crew to Conduct Second Extravehicular Activities

Hainan Launch Center Completes Construction for First Mission

Ten make the cut for China's fourth batch of astronauts

EPIDEMICS
NASA, Partners Conduct Fifth Asteroid Impact Exercise, Release Summary

NASA Asteroid Experts Create Hypothetical Impact Scenario For Exercise

Dimorphos, from Up Close and Far Away

Countdown to Hera launch campaign begins at ESOC

Subscribe Free To Our Daily Newsletters




The content herein, unless otherwise known to be public domain, are Copyright 1995-2024 - Space Media Network. All websites are published in Australia and are solely subject to Australian law and governed by Fair Use principals for news reporting and research purposes. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA news reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. All articles labeled "by Staff Writers" include reports supplied to Space Media Network by industry news wires, PR agencies, corporate press officers and the like. Such articles are individually curated and edited by Space Media Network staff on the basis of the report's information value to our industry and professional readership. Advertising does not imply endorsement, agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. General Data Protection Regulation (GDPR) Statement Our advertisers use various cookies and the like to deliver the best ad banner available at one time. All network advertising suppliers have GDPR policies (Legitimate Interest) that conform with EU regulations for data collection. By using our websites you consent to cookie based advertising. If you do not agree with this then you must stop using the websites from May 25, 2018. Privacy Statement. Additional information can be found here at About Us.